Cutting Edge: Proangiogenic Properties of Alternatively Activated Dendritic Cells

Cutting edge: proangiogenic properties of alternatively activated dendritic cells.

Angiogenesis plays an important role in tissue remodeling and repair during the late phase of inflammation. In the present study, we show that human dendritic cells (DC) that matured in the presence of anti-inflammatory molecules such as calcitriol, PGE2, or IL-10 (alternatively activated DC) selectively secrete the potent angiogenic cytokine vascular endothelial growth factor (VEGF) isoforms V...

CD137 Receptor by Dendritic Cells Cutting Edge: Expression of Functional

Cutting Edge: Progesterone Regulates IFN- Production by Plasmacytoid Dendritic Cells

Cutting Edge Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3

Histone deacetylase (HDAC) inhibition modulates dendritic cell (DC) functions and regulates experimental graft-vs-host disease and other immune-mediated diseases. The mechanisms by which HDAC inhibition modulates immune responses remain largely unknown. STAT-3 is a transcription factor shown to negatively regulate DC functions. In this study we report that HDAC inhibition acetylates and activat...

Signaling Dependent on Glucocorticoid Receptor Alternatively Activated Dendritic Cells Bronchial Epithelial Cells Induce